Abstract
Prosthetic valve endocarditis (PVE) due to Legionella micdadei was diagnosed in a man a year after valve replacement with a bovine xenograft. He did not have pneumonia. The microbiologic diagnosis was established after valvectomy, which was necessitated by failure of empiric antibiotics to eradicate the infection. The fastidious organism grew only on buffered charcoal yeast extract agar and was confirmed as L. micdadei by gene sequence analysis. We believe this to be the first culture-proven case of L. micdadei PVE reported in the literature.
Publication types
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Case Reports
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Anti-Bacterial Agents / therapeutic use*
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Bioprosthesis
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Device Removal
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Endocarditis, Bacterial / drug therapy
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Endocarditis, Bacterial / microbiology
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Heart Valve Prosthesis / adverse effects*
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Heart Valve Prosthesis Implantation* / adverse effects
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Hodgkin Disease / therapy
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Humans
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Immunosuppressive Agents / therapeutic use
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Kidney Failure, Chronic / etiology
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Kidney Failure, Chronic / therapy
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Kidney Transplantation
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Legionella / isolation & purification
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Legionellosis / drug therapy*
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Legionellosis / microbiology
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Levofloxacin*
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Male
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Middle Aged
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Ofloxacin / therapeutic use*
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Prosthesis-Related Infections / drug therapy*
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Prosthesis-Related Infections / microbiology
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Radiation Injuries
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Reoperation
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Treatment Outcome
Substances
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Anti-Bacterial Agents
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Immunosuppressive Agents
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Levofloxacin
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Ofloxacin