Abstract
The two anomers of O-methyl gluco-2,3-digalloyl esters were synthesized and their antimycotic activity toward yeasts of biomedical importance was evaluated. When used at subinhibitory concentration and regardless of stereochemistry at the anomeric carbon, these compounds enhance the antimycotic activity of Amphotericin B.
MeSH terms
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Amphotericin B / pharmacology
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Antifungal Agents / chemical synthesis*
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Antifungal Agents / chemistry
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Antifungal Agents / pharmacology*
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Candida glabrata / drug effects
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Chromatography, High Pressure Liquid
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Esters / chemical synthesis
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Esters / chemistry*
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Esters / pharmacology*
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Gallic Acid / analogs & derivatives*
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Gallic Acid / chemical synthesis
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Gallic Acid / chemistry*
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Methylation
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Molecular Structure
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Stereoisomerism
Substances
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Antifungal Agents
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Esters
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Gallic Acid
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Amphotericin B