Strategies for the NMR-based identification and optimization of allosteric protein kinase inhibitors

Chembiochem. 2005 Sep;6(9):1607-10. doi: 10.1002/cbic.200500100.
No abstract available

MeSH terms

  • Adenine / analogs & derivatives
  • Adenosine Triphosphate / chemistry
  • Adenosine Triphosphate / metabolism
  • Allosteric Regulation / drug effects
  • Ligands
  • Magnetic Resonance Spectroscopy
  • Models, Molecular
  • Protein Kinase Inhibitors / chemistry*
  • Protein Kinase Inhibitors / pharmacology*
  • Protein Kinases / chemistry*
  • Protein Kinases / metabolism*
  • Protein Structure, Tertiary

Substances

  • Ligands
  • Protein Kinase Inhibitors
  • Adenosine Triphosphate
  • Protein Kinases
  • Adenine