[Treatment of primary therapy refractory choriocarcinoma using the EMA-CO protocol]

Geburtshilfe Frauenheilkd. 1992 Apr;52(4):235-8. doi: 10.1055/s-2007-1026136.
[Article in German]

Abstract

This is a report on a 33 year old patient with a metastatic gestational choriocarcinoma. The patient was hospitalized with the picture of a spontaneous left kidney rupture and nephrectomy was performed. Under primary mono-dose methotrexate chemotherapy, the patient showed rapidly progressive metastases in both lungs, liver, right kidney and soft tissue. With the use of multiple-chemotherapy, according to the EMA-CO scheme, we observed complete remission. To date, there has been no indication of any tumour recurrence.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Choriocarcinoma / drug therapy*
  • Choriocarcinoma / pathology
  • Choriocarcinoma / secondary
  • Choriocarcinoma / surgery
  • Combined Modality Therapy
  • Cyclophosphamide / administration & dosage
  • Dactinomycin / administration & dosage
  • Etoposide / administration & dosage
  • Female
  • Follow-Up Studies
  • Humans
  • Hysterectomy, Vaginal
  • Kidney Neoplasms / drug therapy
  • Kidney Neoplasms / pathology
  • Kidney Neoplasms / secondary
  • Kidney Neoplasms / surgery
  • Methotrexate / administration & dosage
  • Nephrectomy
  • Pregnancy
  • Uterine Neoplasms / drug therapy*
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / surgery
  • Vincristine / administration & dosage

Substances

  • Dactinomycin
  • Vincristine
  • Etoposide
  • Cyclophosphamide
  • Methotrexate

Supplementary concepts

  • EMA-CO protocol