Acute endophthalmitis incidence: intravitreal triamcinolone

Arch Ophthalmol. 2005 Aug;123(8):1075-7. doi: 10.1001/archopht.123.8.1075.

Abstract

Objective: To report the incidence of acute postinjection endophthalmitis following intravitreal injection of triamcinolone acetonide (IVTA) as an office procedure.

Methods: Retrospective, noncomparative, consecutive, interventional case series of all patients who had received IVTA at 2 clinical centers between January 1, 2000, and January 30, 2004.

Results: A total of 1006 eyes received IVTA. None of the eyes developed acute, culture-positive, postoperative endophthalmitis in the 6 weeks following the procedure. One patient developed acute, culture-negative, postoperative endophthalmitis 4 days after receiving IVTA, resulting in an incidence of 0.10%. In this case, the presenting symptoms were decreased vision and acute conjunctival erythema. The case was notable for the absence of pain or hypopyon.

Conclusion: Although acute postoperative endophthalmitis may follow IVTA, our experience suggests that this is a relatively uncommon event.

Publication types

  • Multicenter Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Endophthalmitis / chemically induced
  • Endophthalmitis / epidemiology*
  • Endophthalmitis / microbiology
  • Glucocorticoids / administration & dosage*
  • Glucocorticoids / adverse effects
  • Humans
  • Incidence
  • Injections
  • Retinal Diseases / drug therapy
  • Retrospective Studies
  • Texas / epidemiology
  • Triamcinolone Acetonide / administration & dosage*
  • Triamcinolone Acetonide / adverse effects
  • Vitreous Body / drug effects*

Substances

  • Glucocorticoids
  • Triamcinolone Acetonide