Cobalt-catalyzed hydrohydrazination of dienes and enynes: access to allylic and propargylic hydrazides

Org Lett. 2005 Sep 15;7(19):4249-52. doi: 10.1021/ol0517473.

Abstract

[reaction: see text] The cobalt-catalyzed hydrohydrazination reaction of dienes and enynes is presented. Allylic and propargylic hydrazines were obtained in synthetically useful yields (allylic amines, 60-90%; propargylic amines, 47-83%) and good chemo- and regioselectivity.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry
  • Catalysis
  • Cobalt / chemistry*
  • Hydrazines / chemistry*
  • Hydroxylation
  • Molecular Structure
  • Stereoisomerism
  • Water / chemistry*

Substances

  • Alkenes
  • Hydrazines
  • Water
  • Cobalt