Recent advances in the use of phosphorus-centered radicals in organic chemistry

Chem Soc Rev. 2005 Oct;34(10):858-65. doi: 10.1039/b500511f. Epub 2005 Aug 31.

Abstract

This tutorial review aims at presenting recent contributions dealing with organic chemistry of organophosphorus radicals. The first part briefly lays out the physical organic background of such intermediates. In a second part the use of organophosphorus radicals possessing a P-H bond that can undergo homolytic cleavage as alternative mediators is detailed. The third part is focused on radical additions of phosphorus-centered radicals to unsaturated compounds, an old reaction that is being rejuvenated. Lastly, radical eliminations of phosphorus-centered radical are introduced in the fourth part. Most of the latter are relatively novel reactions, and have never been reviewed previously.

Publication types

  • Review

MeSH terms

  • Chemistry, Organic / methods*
  • Chemistry, Organic / trends*
  • Chemistry, Physical / methods*
  • Chemistry, Physical / trends*
  • Free Radicals / chemistry*
  • Organic Chemicals / analysis
  • Organic Chemicals / chemistry*
  • Phosphorus Compounds / analysis
  • Phosphorus Compounds / chemistry*

Substances

  • Free Radicals
  • Organic Chemicals
  • Phosphorus Compounds