Background: Recognition of Wilson disease (WD) is sometimes difficult because of its diverse manifestations. Peripheral neuropathy is rarely reported in the context of WD.
Objective: To report an unusual patient with WD whose initial manifestation was peripheral neuropathy.
Design: Case report.
Setting: Neurology department in a tertiary referral center.
Method: Personal observation.
Result: A 17-year-old man, who was eventually diagnosed with WD, was initially seen with polyneuropathy at least 6 months prior to developing more typical symptoms of WD. Electrophysiological and pathological studies suggested a neuropathy of mixed type. Treatment for WD resulted in clinical and electrophysiological improvement.
Conclusion: Wilson disease may initially appear as a treatable polyneuropathy.