One-step labelling of sphingolipids via a scrambling cross-metathesis reaction

Chem Commun (Camb). 2005 Oct 28:(40):5086-7. doi: 10.1039/b508132g. Epub 2005 Sep 14.

Abstract

The alkyl chain in the backbone of sphingosine derivatives can be exchanged with functionalised (labelled) side chains in a single step under cross-metathesis reaction conditions.

MeSH terms

  • Ceramides / chemistry*
  • Cross-Linking Reagents / chemistry*
  • Methane / chemistry*
  • Methylation
  • Molecular Structure
  • Sphingomyelins / chemistry*
  • Sphingosine / chemistry

Substances

  • Ceramides
  • Cross-Linking Reagents
  • Sphingomyelins
  • Sphingosine
  • Methane