The 2-year stability of neurological soft signs after a first episode of non-affective psychosis

Eur Psychiatry. 2006 Jul;21(5):288-90. doi: 10.1016/j.eurpsy.2005.09.004. Epub 2005 Dec 27.

Abstract

We examined the 2-year stability of neurological soft signs (NSS) in 29 patients after a first episode of psychosis. The numbers of NSS at inclusion and at 2 years follow-up were similar, but there was a significant increase in the numbers of NSS in the sub-group of patients whose dosage of antipsychotic medication had increased over time.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Antipsychotic Agents / adverse effects
  • Antipsychotic Agents / therapeutic use
  • Comorbidity
  • Dose-Response Relationship, Drug
  • Female
  • Follow-Up Studies
  • Humans
  • Longitudinal Studies
  • Male
  • Nervous System Diseases / chemically induced
  • Nervous System Diseases / diagnosis
  • Nervous System Diseases / epidemiology*
  • Neurologic Examination / drug effects
  • Neurologic Examination / statistics & numerical data
  • Risk Factors
  • Schizophrenia / diagnosis
  • Schizophrenia / drug therapy
  • Schizophrenia / epidemiology*
  • Statistics as Topic

Substances

  • Antipsychotic Agents