Abstract
The treatment of hepatoblastoma is an example of the great advances made in paediatric oncology over the past few decades. Formerly a disease with a dreadful prognosis, children now have a 5-year survival rate of over 70%. This has been achieved by advances in surgical techniques and the use of chemotherapy. In future, we hope to be able to improve survival for children with high-risk tumours, and decrease the morbidity associated with treatment in the others.
MeSH terms
-
Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
-
Carboplatin / administration & dosage
-
Child
-
Cisplatin / administration & dosage
-
Clinical Trials as Topic
-
Combined Modality Therapy
-
Cyclophosphamide / administration & dosage
-
Doxorubicin / administration & dosage
-
Fluorouracil / administration & dosage
-
Hepatoblastoma / drug therapy*
-
Hepatoblastoma / surgery*
-
Humans
-
Liver Neoplasms / drug therapy*
-
Liver Neoplasms / surgery*
-
Survival Analysis
-
Vincristine / administration & dosage
Substances
-
Vincristine
-
Doxorubicin
-
Cyclophosphamide
-
Carboplatin
-
Cisplatin
-
Fluorouracil