[Diagnosis and treatment of cytomegalovirus pneumonia after liver transplantation]

Zhonghua Wai Ke Za Zhi. 2005 Dec 1;43(23):1512-5.
[Article in Chinese]

Abstract

Objectives: To investigate the diagnosis and treatment of cytomegalovirus (CMV) pneumonia after liver transplantation.

Methods: Five cases of CMV pneumonia after liver transplantation were analyzed retrospectively. CMV pneumonia was diagnosed according to its clinical manifestation, chest X-ray, and etiologic test. All 5 patients received comprehensive therapy based on anti-virus treatment and immunologic adjustment.

Results: The clinical manifestation of CMV pneumonia after liver transplantation was nonspecific. Its main symptoms included fever, cough, dyspnea, tachycardia, fatigue, hypoxemia and neutropenia. The chest X-ray showed interstitial pneumonia. Sera CMV antigens or antibodies could be detected in the patients. Four patients were cured and 1 patient died.

Conclusions: The clinical manifestation of CMV pneumonia was nonspecific. CMV pneumonia could be diagnosed according to its manifestations, chest X-ray and etiologic test. The comprehensive therapy based on anti-virus treatment and immunologic adjustment was effective for the disease.

Publication types

  • English Abstract
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Combined Modality Therapy
  • Cytomegalovirus Infections / diagnosis*
  • Cytomegalovirus Infections / etiology
  • Cytomegalovirus Infections / therapy
  • Humans
  • Liver Transplantation / adverse effects*
  • Male
  • Middle Aged
  • Pneumonia, Viral / diagnosis*
  • Pneumonia, Viral / etiology
  • Pneumonia, Viral / therapy
  • Postoperative Complications / therapy
  • Retrospective Studies
  • Treatment Outcome