Primary cutaneous CD4+/CD56+ hematodermic neoplasm (blastic NK-cell lymphoma): a report of five cases

Haematologica. 2006 Jan;91(1):143-4.

Abstract

CD4+/CD56+ hematodermic neoplasm (WHO-EORTC) or blastic NK-cell lymphoma (WHO) is a rare aggressive (CD4+)(CD56+)lin- skin-tropic lymphoma of putative early-plasmacytoid dendritic cell origin. We present five cases to highlight the need for greater awareness of this entity amongst pathologists such that aggressive treatment be considered given the generally poor prognosis.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Aged
  • Aged, 80 and over
  • CD4 Antigens
  • CD56 Antigen
  • Humans
  • Killer Cells, Natural / pathology*
  • Lymphoma / diagnosis*
  • Lymphoma / therapy
  • Male
  • Middle Aged
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / pathology*

Substances

  • CD4 Antigens
  • CD56 Antigen