[HIV infection presenting with bilateral optic neuropathy]

Rev Neurol (Paris). 2006 Jan;162(1):95-7. doi: 10.1016/s0035-3787(06)74988-8.
[Article in French]

Abstract

We report the case of a 57-year-old man who presented bilateral subacute and painless optic neuropathy after meningopolyradiculitis revealing a primary human immunodeficiency virus infection. Both antiretroviral and steroid treatments were ineffective. Clinical symptoms and evolutive pattern were consistent with a mechanism of microvascular ischaemia of the optic nerve head. Optic neuropathies related to HIV infection are rare compared to those resulting from opportunistic infections. There are several pathophysiological mechanisms involved.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • AIDS Serodiagnosis
  • Anti-HIV Agents / therapeutic use
  • Antiretroviral Therapy, Highly Active
  • Disease Progression
  • Drug Therapy, Combination
  • Evoked Potentials, Visual
  • Facial Nerve Diseases / etiology
  • HIV Infections / complications
  • HIV Infections / diagnosis*
  • HIV Infections / drug therapy
  • HIV Protease Inhibitors / therapeutic use
  • HIV-1*
  • Humans
  • Ischemia / etiology
  • Lamivudine / therapeutic use
  • Lopinavir
  • Male
  • Meningitis, Viral / etiology
  • Methylprednisolone / therapeutic use
  • Middle Aged
  • Optic Disk / blood supply
  • Optic Nerve Diseases / drug therapy
  • Optic Nerve Diseases / etiology*
  • Polyradiculopathy / etiology
  • Pyrimidinones / therapeutic use
  • Reverse Transcriptase Inhibitors / therapeutic use
  • Ritonavir / therapeutic use
  • Visual Fields
  • Zidovudine / therapeutic use

Substances

  • Anti-HIV Agents
  • HIV Protease Inhibitors
  • Pyrimidinones
  • Reverse Transcriptase Inhibitors
  • Lopinavir
  • Lamivudine
  • Zidovudine
  • Ritonavir
  • Methylprednisolone