Abstract
We quantified Wilm's tumor gene (WT1) using a real time quantitative polymerase chain reaction in 20 adult patients with acute lymphoblastic leukemia at presentation. A WT1 level greater than 906 (median value for the whole series) was a significant predictor of a poor disease-free and overall survival in uni- and multivariate analyses.
Publication types
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Letter
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Research Support, Non-U.S. Gov't
MeSH terms
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Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle Aged
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Precursor Cell Lymphoblastic Leukemia-Lymphoma / diagnosis*
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Precursor Cell Lymphoblastic Leukemia-Lymphoma / genetics
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Predictive Value of Tests
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Prognosis
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RNA, Messenger / analysis
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WT1 Proteins / genetics*
Substances
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RNA, Messenger
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WT1 Proteins