Abstract
Ten new furanocassane-type diterpenes named, caesalpinins H-P (1-9) and norcaesalpinin F (10), were isolated from the CH(2)Cl(2) extract of the seed kernels of Caesalpinia crista, together with 13 known diterpenes. Their structures were determined based on the spectroscopic analysis. Among the isolated compounds, caesalpinin N (7) represents the first example of furanocassane-type diterpene possessing an aldehyde group at C-14.
MeSH terms
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Animals
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Antimalarials / chemistry*
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Antimalarials / isolation & purification
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Antimalarials / pharmacology
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Caesalpinia / chemistry*
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Diterpenes / chemistry*
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Diterpenes / isolation & purification
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Diterpenes / pharmacology
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Indicators and Reagents
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Indonesia
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Magnetic Resonance Spectroscopy
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Plant Extracts / chemistry
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Plasmodium falciparum / drug effects
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Seeds / chemistry
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Spectrometry, Mass, Fast Atom Bombardment
Substances
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Antimalarials
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Diterpenes
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Indicators and Reagents
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Plant Extracts