Abstract
A direct rapid immunohistochemical test (dRIT) was evaluated under field and laboratory conditions to detect rabies virus antigen in frozen and glycerol-preserved field brain samples from northwestern Tanzania. Compared to the direct fluorescent antibody test, the traditional standard in rabies diagnosis, the dRIT was 100% sensitive and specific.
Publication types
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Comparative Study
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Evaluation Study
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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Animals
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Animals, Domestic / virology*
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Animals, Wild / virology*
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Antigens, Viral / analysis*
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Brain / virology
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Cats
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Cattle
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Dogs
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Glycerol
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Immunohistochemistry / methods*
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Population Surveillance
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Rabies / diagnosis
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Rabies / epidemiology
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Rabies / veterinary*
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Rabies / virology
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Rabies virus / isolation & purification*
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Sensitivity and Specificity
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Tanzania / epidemiology
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Time Factors
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Tissue Preservation