Expression of Chlamydia trachomatis inclusion membrane protein genes IncB and IncC in Escherichia coli

Biochemistry (Mosc). 2006 Mar;71(3):262-9. doi: 10.1134/s0006297906030059.

Abstract

In this study, we have cloned the Chlamydia trachomatis genes incB and incC into the expression plasmid vectors from pET series for the subsequent isolation of recombinant proteins. As a result, we have obtained the first full-length recombinant C. trachomatis proteins IncB and IncC, which can be used for following antibody production and for study of their protein-protein interaction.

MeSH terms

  • Amino Acid Sequence
  • Animals
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Chlamydia trachomatis
  • Escherichia coli / genetics
  • Escherichia coli / metabolism*
  • Female
  • Gene Expression Regulation, Bacterial
  • Humans
  • Membrane Proteins / genetics
  • Membrane Proteins / metabolism*
  • Molecular Sequence Data
  • Peptide Fragments / genetics
  • Peptide Fragments / metabolism
  • Polymorphism, Genetic
  • Recombinant Fusion Proteins / genetics
  • Recombinant Fusion Proteins / metabolism
  • Thioredoxins / genetics
  • Thioredoxins / metabolism

Substances

  • Bacterial Proteins
  • Membrane Proteins
  • Peptide Fragments
  • Recombinant Fusion Proteins
  • Thioredoxins