Abstract
Introduction:
Human herpesvirus 6 (HHV-6), the causative agent of the common exanthem subitum, is a known cause of central nervous system infection in immunocompromised patients. It has been suggested that HHV-6 participate in the development of drug-induced hypersensitivity syndrome.
Case report:
We reported a case of HHV-6 encephalitis associated with hypersensitivity syndrome induced by trimethoprim-sulfamethoxazole in a 72-year-old HIV-negative woman.
Discussion:
Our case confirmed that reactivation of HHV-6 infection may contribute to the development of the hypersensitivity syndrome.
Publication types
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Case Reports
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English Abstract
MeSH terms
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Aged
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Anti-Infective Agents / adverse effects*
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Antiviral Agents / therapeutic use
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Drug Hypersensitivity / drug therapy
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Drug Hypersensitivity / etiology*
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Encephalitis, Viral / complications*
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Encephalitis, Viral / drug therapy
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Female
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Ganciclovir / therapeutic use
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Herpesvirus 6, Human / isolation & purification*
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Humans
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Roseolovirus Infections / complications*
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Roseolovirus Infections / drug therapy
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Syndrome
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Treatment Outcome
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Trimethoprim, Sulfamethoxazole Drug Combination / adverse effects*
Substances
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Anti-Infective Agents
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Antiviral Agents
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Trimethoprim, Sulfamethoxazole Drug Combination
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Ganciclovir