Heart rate-corrected QT interval duration is significantly associated with blood pressure in Chinese hypertensives

J Electrocardiol. 2006 Apr;39(2):206-10. doi: 10.1016/j.jelectrocard.2005.08.007. Epub 2005 Nov 9.

Abstract

Introduction: Many studies demonstrated that a prolonged heart rate-corrected QT interval (QTc) increases the risk of malignant ventricular arrhythmias and sudden death.

Methods: We measured the electrocardiogram and blood pressure of 1480 hypertensive patients and assessed the relationship between the length of QTc and blood pressure.

Results: The mean QTc is longer in female than in male participants. There was a positive association between QTc and blood pressure in both men and women. The estimated increase in systolic and diastolic blood pressure for each 100-millisecond increase in QTc was 6.4 and 5.0 mm Hg in men and 3.7 and 2.5 mm Hg in women, respectively.

Conclusion: Our study demonstrated a significant positive relationship between the QTc interval and baseline blood pressure in a Chinese hypertensive population.

MeSH terms

  • Adult
  • Aged
  • Chi-Square Distribution
  • China
  • Electrocardiography
  • Female
  • Heart Rate / physiology
  • Humans
  • Hypertension / physiopathology*
  • Long QT Syndrome / physiopathology*
  • Male
  • Middle Aged
  • Sex Factors
  • Surveys and Questionnaires