Varicella zoster virus meningitis complicating sodium stibogluconate treatment for cutaneous leishmaniasis

Am J Trop Med Hyg. 2006 Apr;74(4):591-2.

Abstract

Sodium stibogluconate (Pentostam(R); GlaxoSmithKline) is a pentavalent antimonial compound used in the treatment of leishmaniasis, which has an association with reactivation of varicella zoster virus (VZV). We report the first known case of an immunocompetent adult who developed VZV aseptic meningitis and dermatomal herpes zoster during treatment with sodium stibogluconate.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Animals
  • Antimony Sodium Gluconate / adverse effects*
  • Antiprotozoal Agents / adverse effects*
  • Diagnosis, Differential
  • Encephalitis, Varicella Zoster / etiology*
  • Herpes Zoster
  • Humans
  • Leishmania major / isolation & purification*
  • Leishmaniasis, Cutaneous / diagnosis*
  • Leishmaniasis, Cutaneous / drug therapy*
  • Leishmaniasis, Cutaneous / pathology
  • Male
  • Skin Diseases, Viral / etiology

Substances

  • Antiprotozoal Agents
  • Antimony Sodium Gluconate