T regulatory cell suppression of colitis: the role of TGF-beta

Gut. 2006 May;55(5):604-6. doi: 10.1136/gut.2005.083592.

Abstract

Transforming growth factor β (TGF‐β) and interleukin 2 may be involved in IBD peripheral regulatory T cell pathophysiology, raising the possibility of therapeutic application of TGF‐β induced regulatory T cells in IBD patients

Publication types

  • Comment

MeSH terms

  • Colitis / immunology*
  • Humans
  • Immunosuppression Therapy
  • Interleukin-2 / immunology
  • T-Lymphocytes, Regulatory / immunology*
  • Thymus Gland / immunology
  • Transforming Growth Factor beta / immunology*

Substances

  • Interleukin-2
  • Transforming Growth Factor beta