Ureteral complications in the renal transplant recipient after laparoscopic living donor nephrectomy

Eur Urol. 2006 Sep;50(3):535-40; discussion 540-1. doi: 10.1016/j.eururo.2006.03.025. Epub 2006 Mar 29.

Abstract

Objectives: We report on ureteral and surgical complications in our first 110 consecutive recipients of kidneys procured with laparoscopic living donor nephrectomy (LLDN).

Methods: The records of all living donor transplants with LLDN performed between February 1999 and December 2004, including 10 pediatric transplants, were reviewed retrospectively. Three urologists performed LLDN using a pure laparoscopic non-hand-assisted transperitoneal technique. Kidney transplantation was performed in a standard fashion. For ureteroneocystostomy, the intravesical Politano-Leadbetter (P-L) technique was used.

Results: Two-year patient and graft survival was 99% and 98%, respectively. Serum creatinine at 12 months was 1.36+/-0.1mg/dl in adult and 0.99+/-0.23 mg/dl in pediatric recipients. Nineteen right donor kidneys were transplanted into adult recipients. Surgical complications included three symptomatic lymphoceles, one peritransplant haematoma and one kinking of a lower pole artery. All five (4.5%) ureteral complications occurred in adult recipients with a mean age of 33.2+/-2.8 years. The incidence of ureteral complications was not clustered around the early phase of our LLDN experience. Of the three (2.7%) patients diagnosed with ureteral obstruction, two required ureteral reimplantation, and one was managed conservatively. Another two patients (1.8%) with a urinary leak received a double J stent and a cystostomy catheter for 3 and 5 months, respectively. Of the five patients with a ureteral complication, three had received a donor kidney with more than one renal artery.

Conclusions: LLDN combined with the intravesical (P-L) ureteral implantation technique provides excellent graft outcomes with low recipient morbidity. Renal artery multiplicity may increase the risk of ureteral complications.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Incidence
  • Kidney Transplantation / adverse effects*
  • Kidney Transplantation / methods*
  • Kidney Transplantation / mortality
  • Laparoscopy / methods*
  • Living Donors / statistics & numerical data
  • Male
  • Middle Aged
  • Nephrectomy / methods*
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / mortality
  • Retrospective Studies
  • Survival Analysis
  • Transplantation / statistics & numerical data
  • Treatment Outcome
  • Ureteral Diseases / epidemiology*
  • Ureteral Diseases / etiology