Erythromycin and clindamycin resistance in group B streptococcal clinical isolates

Antimicrob Agents Chemother. 2006 May;50(5):1875-7. doi: 10.1128/AAC.50.5.1875-1877.2006.

Abstract

Erythromycin (EM) and clindamycin (CM) susceptibility testing was performed on 222 clinical isolates of group B Streptococcus. A multiplex PCR assay was used to detect the ermB, ermTR, and mefA/E antibiotic resistance genes. These results were compared to the phenotypes as determined by the standard EM/CM double disk diffusion assay.

Publication types

  • Comparative Study

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Clindamycin / pharmacology*
  • Drug Resistance, Multiple, Bacterial / genetics*
  • Erythromycin / pharmacology*
  • Genes, Bacterial
  • Humans
  • Microbial Sensitivity Tests
  • Streptococcal Infections / microbiology*
  • Streptococcus agalactiae / drug effects*
  • Streptococcus agalactiae / genetics
  • Streptococcus agalactiae / isolation & purification

Substances

  • Anti-Bacterial Agents
  • Clindamycin
  • Erythromycin