End points in clinical trials: are they moving the goalposts?

Heart. 2006 Jul;92(7):870-2. doi: 10.1136/hrt.2005.082024.

Abstract

In selecting and defining composite end points in clinical trials, are we trading off clinical significance for statistical significance?

Publication types

  • Comment
  • Editorial

MeSH terms

  • Angioplasty, Balloon, Coronary / methods
  • Clinical Trials as Topic / standards*
  • Coronary Artery Bypass / methods
  • Hemorrhage / etiology
  • Humans
  • Myocardial Infarction / diagnosis
  • Myocardial Infarction / therapy*
  • Safety Management
  • Treatment Outcome