Abstract
Although the association between inflammatory bowel disease and gastrointestinal infections has been suggested, the mechanisms involved in the pathogenesis of Crohn's disease (CD) are still undetermined. We report the case of a man, who presented with mesenteric adenitis initially due to a Yersinia pseudotubercolosis infection, who was later diagnosed with Crohn's disease. This case is in keeping with recent evidence in the literature which suggests that CD is a disease linked to abnormal immune responses to enteric bacteria in genetically susceptible individuals.
MeSH terms
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Adult
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Antibodies, Bacterial / immunology
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Crohn Disease / etiology*
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Crohn Disease / genetics
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Crohn Disease / pathology
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Genetic Predisposition to Disease
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Histocompatibility Antigens Class II / immunology
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Humans
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Ileal Diseases / etiology
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Ileal Diseases / genetics
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Ileal Diseases / pathology
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Ileum / pathology
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Male
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Mesenteric Lymphadenitis / complications*
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Mesenteric Lymphadenitis / immunology
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Mesenteric Lymphadenitis / microbiology*
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Yersinia pseudotuberculosis / immunology
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Yersinia pseudotuberculosis / pathogenicity*
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Yersinia pseudotuberculosis Infections / complications*
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Yersinia pseudotuberculosis Infections / immunology
Substances
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Antibodies, Bacterial
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Histocompatibility Antigens Class II