Species differences in the activation of mianserin to a cytotoxic metabolite

Drug Metab Dispos. 1991 Jul-Aug;19(4):841-3.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Biotransformation
  • Chromatography
  • Guinea Pigs
  • Humans
  • Male
  • Mianserin / analogs & derivatives
  • Mianserin / metabolism
  • Mianserin / pharmacokinetics*
  • Mianserin / toxicity
  • Microsomes, Liver / metabolism
  • Rabbits
  • Rats
  • Species Specificity

Substances

  • Mianserin
  • desmethylmianserin