Numerical simulation of wave propagation in cancellous bone

Ultrasonics. 2006 Dec 22:44 Suppl 1:e239-43. doi: 10.1016/j.ultras.2006.06.042. Epub 2006 Jun 30.

Abstract

Numerical simulation of wave propagation is performed through 31 3D volumes of trabecular bone. These volumes were reconstructed from high synchrotron microtomography experiments and are used as the input geometry in a simulation software developed in our laboratory. The simulation algorithm accounts for propagation into both the saturating fluid and bone but absorption is not taken into account. We show that 3D simulation predicts phenomena observed experimentally in trabecular bones : linear frequency dependence of attenuation, increase of attenuation and speed of sound with the bone volume fraction, negative phase velocity dispersion in most of the specimens, propagation of fast and slow wave depending on the orientation of the trabecular network compared to the direction of propagation of the ultrasound. Moreover, the predicted attenuation is in very close agreement with the experimental one measured on the same specimens. Coupling numerical simulation with real bone architecture therefore provides a powerful tool to investigate the physics of ultrasound propagation in trabecular structures.

MeSH terms

  • Algorithms
  • Bone and Bones / diagnostic imaging*
  • Bone and Bones / physiology*
  • Computer Simulation
  • Elasticity
  • Finite Element Analysis
  • Humans
  • Image Enhancement / methods*
  • Image Interpretation, Computer-Assisted / methods*
  • Imaging, Three-Dimensional / methods*
  • In Vitro Techniques
  • Models, Biological*
  • Numerical Analysis, Computer-Assisted
  • Radiation Dosage
  • Radiometry / methods
  • Reproducibility of Results
  • Scattering, Radiation
  • Sensitivity and Specificity
  • Ultrasonography / methods*
  • Viscosity