Serotypes, genotypes, and antibiotic susceptibility profiles of group B streptococci causing neonatal sepsis and meningitis before and after introduction of antibiotic prophylaxis

Pediatr Infect Dis J. 2006 Oct;25(10):945-8. doi: 10.1097/01.inf.0000237821.65559.08.

Abstract

We studied the characteristics of strains isolated from neonates with group B streptococci sepsis and meningitis, before and after the introduction of antibiotic prophylaxis in The Netherlands. In 1999, 1 year after this introduction the serotype and genotype distribution and the susceptibility patterns of the GBS strains had not changed. Penicillins remain drugs of first choice to prevent and treat neonatal GBS disease.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / pharmacology*
  • Antibiotic Prophylaxis*
  • Bacterial Typing Techniques
  • Genotype
  • Humans
  • Infant, Newborn
  • Meningitis, Bacterial / microbiology*
  • Meningitis, Bacterial / prevention & control
  • Microbial Sensitivity Tests
  • Netherlands
  • Sepsis / microbiology*
  • Serotyping
  • Streptococcal Infections / microbiology*
  • Streptococcal Infections / prevention & control
  • Streptococcus agalactiae / classification*
  • Streptococcus agalactiae / drug effects*
  • Streptococcus agalactiae / isolation & purification

Substances

  • Anti-Bacterial Agents