LRRK2 mutations on Crete: R1441H associated with PD evolving to PSP

Neurology. 2006 Oct 24;67(8):1518-9. doi: 10.1212/01.wnl.0000239829.33936.73.

Authors

Cleanthe Spanaki¹, Helen Latsoudis, Andreas Plaitakis

Affiliation

¹ Department of Neurology, University of Crete, Medical School, Heraklion, Crete, Greece.

PMID: 17060595
DOI: 10.1212/01.wnl.0000239829.33936.73

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Age of Onset
Aged
Aged, 80 and over
Arginine
Cohort Studies
Dementia / etiology
Disease Progression
Female
Genetic Predisposition to Disease*
Greece
Histidine
Humans
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Male
Middle Aged
Mutation*
Parkinson Disease / epidemiology
Parkinson Disease / genetics*
Parkinson Disease / physiopathology
Parkinson Disease / psychology
Pedigree
Protein Serine-Threonine Kinases / genetics*
Supranuclear Palsy, Progressive / epidemiology
Supranuclear Palsy, Progressive / genetics*

Substances

Histidine
Arginine
LRRK2 protein, human
Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
Protein Serine-Threonine Kinases