Shiga toxin and Shiga toxin-encoding phage do not facilitate Escherichia coli O157:H7 colonization in sheep

Appl Environ Microbiol. 2007 Jan;73(1):344-6. doi: 10.1128/AEM.01328-06. Epub 2006 Nov 3.

Abstract

Isogenic strains of Escherichia coli O157:H7, missing either stx(2) or the entire Stx2-encoding phage, were compared with the parent strain for their abilities to colonize sheep. The absence of the phage or of the Shiga toxin did not significantly impact the magnitude or duration of shedding of E. coli O157:H7.

Publication types

  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Coliphages / genetics*
  • Coliphages / metabolism
  • Colony Count, Microbial
  • Escherichia coli O157 / genetics
  • Escherichia coli O157 / growth & development*
  • Escherichia coli O157 / virology
  • Feces / microbiology
  • Gene Deletion
  • Sheep / microbiology*
  • Shiga Toxin 2 / genetics*
  • Shiga Toxin 2 / metabolism*

Substances

  • Shiga Toxin 2