Improved resolution in (13)C solid-state spectra through spin-state-selection

René Verel; Theofanis Manolikas; Ansgar B Siemer; Beat H Meier

doi:10.1016/j.jmr.2006.09.024

Improved resolution in (13)C solid-state spectra through spin-state-selection

J Magn Reson. 2007 Feb;184(2):322-9. doi: 10.1016/j.jmr.2006.09.024. Epub 2006 Nov 7.

Authors

René Verel¹, Theofanis Manolikas, Ansgar B Siemer, Beat H Meier

Affiliation

¹ Physical Chemistry, ETH Zurich, Wolfgang-Pauli-Strasse 10, CH-8093 Zurich, Switzerland.

PMID: 17088090
DOI: 10.1016/j.jmr.2006.09.024

Abstract

The application of a spin-state-selective coherence transfer experiment (INADEQUATE-SSS) to solid-state NMR spectroscopy is described. Two-dimensional (13)C double-quantum/single-quantum spectra without J splittings in both dimensions lead to enhanced spectral resolution. The method is demonstrated to significantly improve the spectral resolution of the crowded C'-C(alpha) region of two proteins.

Publication types

Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Algorithms*
Carbon Isotopes / chemistry*
Computer Simulation
Magnetic Resonance Spectroscopy / methods*
Models, Chemical*
Sensitivity and Specificity
Spin Labels

Substances

Carbon Isotopes
Spin Labels