Liver transplantation for fulminant hepatitis related to nevirapine therapy

Liver Transpl. 2006 Dec;12(12):1880-2. doi: 10.1002/lt.20985.

Abstract

Drug-induced hepatotoxicity is an important cause of hepatocellular injury. Non-nucleoside retroviral transcriptase inhibitors are known to cause hepatotoxicity. We describe a detailed case of fulminant hepatitis induced by nevirapine (Viramune) and treated by liver transplantation.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anti-HIV Agents / adverse effects*
  • Anti-HIV Agents / therapeutic use
  • Female
  • HIV Infections / drug therapy
  • HIV-1
  • Hepatitis / etiology
  • Hepatitis / pathology
  • Hepatitis / surgery*
  • Humans
  • Liver Failure, Acute / chemically induced
  • Liver Failure, Acute / pathology
  • Liver Failure, Acute / surgery*
  • Liver Transplantation*
  • Nevirapine / adverse effects*
  • Nevirapine / therapeutic use
  • Treatment Outcome

Substances

  • Anti-HIV Agents
  • Nevirapine