Pediatric gastroesophageal varices: treatment strategy and long-term results

J Pediatr Surg. 2006 Dec;41(12):1980-3. doi: 10.1016/j.jpedsurg.2006.08.022.

Abstract

Background/purpose: There are various treatment strategies for gastroesophageal varices in children. We studied the therapeutic value of endoscopic variceal clipping (EVC) and ligation (EVL).

Methods: Four hundred ninety-nine endoscopic examinations performed between 1991 and 2005 were retrospectively analyzed. F2 and F3 varices with red color signs on follow-up endoscopy were treated with prophylactic EVC. In variceal rupture cases, EVC and EVL were used in combination.

Results: Eighty-two prophylactic EVCs were done, and variceal progression was prevented in 89.9%. However, some patients had persistent red color signs and required frequent EVC. Ten emergent procedures were done for variceal rupture, and, in 4 cases, EVL was used to arrest massive variceal bleeding. Five patients developed bleeding during follow-up cause by rupture of gastric fundal varices, which probably had been aggravated by prior treatment for esophageal varices.

Conclusions: The control of gastroesophageal varices by routine EVC was satisfactory. However, ruptures during follow-up suggested the importance of controlling gastric fundal varices. Endoscopic variceal ligation is a simple, effective, and safe treatment tool, particularly for ruptured varices. However, it is difficult to treat gastric fundal varices with EVL; this disadvantage of EVL can be overcome by the concomitant use of EVC.

MeSH terms

  • Adolescent
  • Adult
  • Child
  • Child, Preschool
  • Esophageal and Gastric Varices / complications
  • Esophageal and Gastric Varices / therapy*
  • Gastrointestinal Hemorrhage / etiology
  • Gastrointestinal Hemorrhage / therapy*
  • Gastroscopy*
  • Humans
  • Infant
  • Ligation
  • Retrospective Studies
  • Rupture, Spontaneous
  • Surgical Instruments
  • Time Factors
  • Treatment Outcome