Screening for acute HIV infection: lessons learned

Clin Infect Dis. 2007 Feb 1;44(3):459-61. doi: 10.1086/510747. Epub 2006 Dec 20.

Abstract

Human immunodeficiency virus (HIV) nucleic acid testing is increasingly being used by researchers and public health screening programs to identify highly infectious, HIV antibody-negative individuals with acute HIV infection. We present cases to illustrate unusual instances of acute HIV screening, which include "window period" testing and the discovery of low-level HIV RNA.

Publication types

  • Case Reports
  • Research Support, N.I.H., Extramural

MeSH terms

  • Acute Disease
  • False Negative Reactions
  • HIV / isolation & purification
  • HIV Antibodies / blood*
  • HIV Infections / diagnosis*
  • HIV Infections / genetics
  • HIV Seronegativity*
  • HIV Seropositivity*
  • Humans
  • Mass Screening
  • Nucleic Acid Amplification Techniques / methods
  • RNA, Viral / blood*
  • Sensitivity and Specificity
  • Viremia / diagnosis

Substances

  • HIV Antibodies
  • RNA, Viral