Perimetric sensitivity with the micro perimeter 1 and retinal thickness in patients with branch retinal vein occlusion

Am J Ophthalmol. 2007 Feb;143(2):342-4. doi: 10.1016/j.ajo.2006.09.034. Epub 2006 Oct 17.

Abstract

Purpose: To evaluate the relationship between retinal sensitivity and thickness of the macular edema associated with branch retinal vein occlusion (BRVO).

Design: Prospective case series.

Methods: We prospectively examined 15 eyes of 15 patients with macular edema associated with BRVO. In each patient, retinal sensitivity in the macular area was examined with the Micro Perimeter 1 (MP-1); retinal thickness was measured by optical coherence tomography (OCT). Eyes with marked retinal hemorrhage or macular nonperfusion were excluded from the current study.

Results: Retinal sensitivity measured with the MP-1 was significantly correlated with retinal thickness in the fovea (R(2) = 0.460) and in all extrafoveal regions (R(2) = 0.383 to 0.794). In four eyes treated with triamcinolone acetonide, retinal sensitivity showed marked improvement in parallel with the reduction of the macular edema.

Conclusions: Retinal sensitivity in the macular area correlates linearly and negatively with increased retinal thickness in eyes with BRVO.

MeSH terms

  • Aged
  • Female
  • Glucocorticoids / therapeutic use
  • Humans
  • Macular Edema / drug therapy
  • Macular Edema / etiology
  • Macular Edema / physiopathology*
  • Male
  • Middle Aged
  • Prospective Studies
  • Retina / drug effects
  • Retina / physiopathology*
  • Retinal Vein Occlusion / complications
  • Retinal Vein Occlusion / drug therapy
  • Retinal Vein Occlusion / physiopathology*
  • Tomography, Optical Coherence
  • Triamcinolone Acetonide / therapeutic use
  • Visual Field Tests / methods*

Substances

  • Glucocorticoids
  • Triamcinolone Acetonide