Complications of laparoscopic living donor nephrectomy and their management: the UCLA experience

Urology. 2007 Jan;69(1):49-52. doi: 10.1016/j.urology.2006.09.030.

Abstract

Objectives: Because of the shortage of cadaveric kidneys, laparoscopic living donor nephrectomy (LLDN) has become a more common option for transplant recipients. The complication rate has been reported at 6.4% to 16.5%. We present the initial University of California, Los Angeles experience with the complications and their management during LLDN.

Methods: From January 2000 to December 2005, a single surgeon performed 300 consecutive LLDNs at our institution. A committee of urologists, nephrologists, and support staff approved each donor before surgery. After LLDN was completed, the patients received 30 mg of ketorolac intravenously every 6 hours until discharge. We reviewed the intraoperative and postoperative complications and their management at our institution.

Results: Three patients required open conversion, for an overall conversion rate of 1%. Two of the three conversions were a result of a major vascular complication (0.6%). The first major vascular complication resulted from an endovascular stapler malfunction during transection of an accessory left renal artery. The second vascular complication was a Veress needle injury to the left common iliac artery. Three postoperative major complications (1%) occurred, including 1 case of rhabdomyolysis and 2 cases of chylous ascites. Also, 7 minor postoperative complications (2.3%) occurred. Our overall complication rate was 4%. No patients died, and the mean hospital stay was 1.1 days.

Conclusions: Our results have shown that LLDN is a safe procedure associated with low morbidity and a quick recovery. Appropriate patient selection is essential to ensure the safety of this procedure.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Female
  • Humans
  • Incidence
  • Intraoperative Complications / epidemiology
  • Intraoperative Complications / etiology
  • Intraoperative Complications / therapy
  • Laparoscopy*
  • Living Donors*
  • Male
  • Middle Aged
  • Nephrectomy / adverse effects*
  • Nephrectomy / methods*
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology
  • Postoperative Complications / therapy