Abstract
Two examples are presented for the application of the total effective xenoestrogen burden as biomarker of chemical exposure measured in tissue samples from patients recruited for two case-control studies. The first study focused on environmental chemicals with hormone mimicking activity, the so-called environmental estrogens, and their participation in the etiology of breast cancer. The second study investigated mother-child exposure to persistent organochlorine chemicals and assessed their combined effect on the risk of male urogenital malformations in the newborn.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Adipose Tissue / chemistry*
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Adult
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Aged
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Biomarkers
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Breast Neoplasms / epidemiology
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Case-Control Studies
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Environmental Exposure / adverse effects
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Environmental Monitoring / methods*
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Epidemiological Monitoring
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Estrogens / analysis*
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Female
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Health Surveys
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Humans
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Hydrocarbons, Chlorinated / analysis
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Infant, Newborn
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Male
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Maternal Exposure
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Middle Aged
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Pesticides / analysis
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Placenta / chemistry
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Pregnancy
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Prenatal Exposure Delayed Effects*
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Spain
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Urogenital Abnormalities / epidemiology*
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Xenobiotics / analysis*
Substances
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Biomarkers
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Estrogens
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Hydrocarbons, Chlorinated
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Pesticides
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Xenobiotics