Long-term visual outcome of childhood blepharokeratoconjunctivitis

Am J Ophthalmol. 2007 Mar;143(3):528-9. doi: 10.1016/j.ajo.2006.09.058. Epub 2006 Nov 9.

Abstract

Purpose: To assess the visual outcome of childhood blepharokeratoconjunctivitis.

Design: Retrospective noncomparative case series.

Methods: We reviewed visual acuity and corneal examination results for 23 patients (mean age 19 +/- 4 years, range, 11 to 26 years) who had healed more than three years previously (up to 15 years).

Results: The disease involved 29 eyes and was unilateral in 17 children. Corneal sequelae (neovascularization or scars) involved 18 eyes (62%) of 15 children (65%). Mean best-corrected visual acuity was 20/25 (range, 20/100 to 20/20). Best-corrected visual acuity was no more than 20/30 in seven eyes (24%) of seven children (30%). Fifteen eyes (52%) of 13 children (45%) had astigmatisms of at least 0.75 diopters attributable to corneal scars.

Conclusions: Corneal and visual sequelae are frequent in childhood blepharokeratoconjunctivitis. Early diagnosis and specific treatment are mandatory.

MeSH terms

  • Adolescent
  • Adult
  • Anti-Bacterial Agents / therapeutic use
  • Blepharitis / drug therapy
  • Blepharitis / physiopathology*
  • Child
  • Drug Therapy, Combination
  • Female
  • Follow-Up Studies
  • Fusidic Acid / therapeutic use
  • Humans
  • Keratoconjunctivitis / drug therapy
  • Keratoconjunctivitis / physiopathology*
  • Macrolides / therapeutic use
  • Male
  • Retrospective Studies
  • Tetracycline / therapeutic use
  • Visual Acuity / physiology*

Substances

  • Anti-Bacterial Agents
  • Macrolides
  • Fusidic Acid
  • Tetracycline