Four cases of Hb Q-H disease found in Southern China

Hemoglobin. 2007;31(1):109-11. doi: 10.1080/03630260601059340.

Abstract

Four Chinese patients with Hb Q-H disease were identified during thalassemia screening. The main hematological characteristics of Hb Q-H disease are that Hb A is absent, and Hb Q-Thailand (also known as G-Taichung, Mahidol, Kurashiki-I and Asabara) accounts for the majority of the total hemoglobin (Hb). The phenotype of this disorder is similar to that of deletional Hb H (beta4) disease.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Anemia / etiology
  • China / ethnology
  • Female
  • Hemoglobin H / genetics*
  • Hemoglobin H / isolation & purification
  • Hemoglobins, Abnormal / genetics*
  • Humans
  • Male
  • Mass Screening
  • Phenotype
  • Pregnancy
  • Prenatal Care
  • Sequence Analysis, DNA
  • alpha-Thalassemia / complications
  • alpha-Thalassemia / genetics*

Substances

  • Hemoglobins, Abnormal
  • hemoglobin Q Thailand
  • Hemoglobin H