Major role of levofloxacin in the treatment of a case of Listeria monocytogenes meningitis

Diagn Microbiol Infect Dis. 2007 May;58(1):137-9. doi: 10.1016/j.diagmicrobio.2006.11.010. Epub 2007 Mar 26.

Abstract

We report a case of acute bacterial meningitis due to Listeria monocytogenes whose successful treatment was mainly attributable to high-dose levofloxacin therapy (500 mg iv bid). This supports the hypothesis that levofloxacin may be an effective option for the treatment of listerial meningitis.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Anti-Bacterial Agents / therapeutic use*
  • Cerebrospinal Fluid / microbiology
  • Female
  • Humans
  • Levofloxacin*
  • Listeria monocytogenes / drug effects*
  • Listeria monocytogenes / isolation & purification
  • Listeriosis / drug therapy
  • Listeriosis / microbiology
  • Meningitis, Listeria / drug therapy*
  • Meningitis, Listeria / microbiology
  • Ofloxacin / therapeutic use*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Levofloxacin
  • Ofloxacin