Toxoplasma gondii antibodies in cancer patients

Cancer Lett. 2007 Aug 28;254(1):71-4. doi: 10.1016/j.canlet.2007.02.011. Epub 2007 Mar 21.

Abstract

To determine Toxoplasma gondii antibodies in cancer patients, 267 cancer patients were studied using ELISA and higher positivity rates of T. gondii IgG were detected than the control. The positivity rates of T. gondii IgG in nasopharyngeal carcinoma, rectal cancer groups were significantly higher than the other cancer groups, but the differences in IgM positivity rates were not significant, demonstrating that there is a likely association between T. gondii infection and some kinds of cancer, especially nasopharyngeal carcinoma and rectal cancer.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Animals
  • Antibodies, Protozoan / blood*
  • Enzyme-Linked Immunosorbent Assay
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Immunoglobulin M / blood
  • Male
  • Middle Aged
  • Nasopharyngeal Neoplasms / blood
  • Nasopharyngeal Neoplasms / complications
  • Neoplasms / blood*
  • Neoplasms / complications
  • Rectal Neoplasms / blood
  • Rectal Neoplasms / complications
  • Toxoplasma / growth & development
  • Toxoplasma / immunology*
  • Toxoplasmosis / blood*
  • Toxoplasmosis / complications
  • Toxoplasmosis / parasitology

Substances

  • Antibodies, Protozoan
  • Immunoglobulin G
  • Immunoglobulin M