Abstract
Oxygen-free radicals, more generally known as reactive oxygen species (ROS) along with nitrogen species (RNS) are well recognised for playing a dual role both deleterious and beneficial species. The cumulative generation of ROS/RNS through either endogenous or exogenous insults is termed oxidative stress and is common for many types of diseases that are linked with altered redox regulation of cellular signalling pathways.
MeSH terms
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Animals
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Antioxidants / pharmacology
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Antioxidants / therapeutic use*
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Humans
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Oxidation-Reduction / drug effects
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Oxidative Stress / drug effects*
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Oxidative Stress / physiology
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Reactive Nitrogen Species / antagonists & inhibitors
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Reactive Nitrogen Species / metabolism
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Reactive Oxygen Species / antagonists & inhibitors
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Reactive Oxygen Species / metabolism
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Signal Transduction / drug effects
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Signal Transduction / physiology
Substances
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Antioxidants
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Reactive Nitrogen Species
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Reactive Oxygen Species