Abstract
The O-acyl isopeptide method has recently received attention as an efficient synthetic method for peptides. Herein, forty kinds of "O-acyl isodipeptide unit" Boc-Ser/Thr(Fmoc-Xaa)-OH (1-40) were effectively synthesized in two-steps without epimerization. The O-acyl isodipeptide units are important building blocks to enable the routine use of the O-acyl isopeptide method.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Amino Acid Sequence
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Chemistry, Organic / methods*
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Chromatography, High Pressure Liquid
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Dipeptides / analysis
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Dipeptides / chemical synthesis*
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Dipeptides / chemistry
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Esterification
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Influenza A virus / chemistry
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Isomerism
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Molecular Sequence Data
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Oligopeptides / analysis
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Oligopeptides / chemical synthesis*
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Oligopeptides / chemistry