2'-N-(pyren-1-yl)acetyl-2'-amino-alpha-L-LNA: synthesis and detection of single nucleotide mismatches in DNA and RNA targets

Chembiochem. 2007 Jul 9;8(10):1122-5. doi: 10.1002/cbic.200700144.

Authors

T Santhosh Kumar¹, Jesper Wengel, Patrick J Hrdlicka

Affiliation

¹ Nucleic Acid Center, Department of Physics and Chemistry, University of Southern Denmark, 5230 Odense M, Denmark.

PMID: 17551917
DOI: 10.1002/cbic.200700144

No abstract available

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Base Pair Mismatch*
DNA / chemistry*
Genetic Techniques
Models, Chemical
Models, Genetic
Nucleic Acid Conformation
Nucleic Acid Hybridization
Nucleic Acids / chemistry*
Nucleotides / chemistry*
RNA / chemistry*
Spectrometry, Fluorescence
Temperature
Thermodynamics
Thymidine Monophosphate / analogs & derivatives*
Thymidine Monophosphate / chemistry

Substances

2'-N-(pyren-1-yl)acetyl-2'-amino-alpha-L-LNA
Nucleic Acids
Nucleotides
Thymidine Monophosphate
RNA
DNA