[Hyperemesis gravidarum: a rare cause of Wernicke encephalopathy]

Presse Med. 2007 Dec;36(12 Pt 1):1759-61. doi: 10.1016/j.lpm.2007.05.021. Epub 2007 Jun 14.
[Article in French]

Abstract

Introduction: Wernicke encephalopathy - most often observed in alcoholic patients - is due to severe thiamine deficiency.

Case: We report here the case of a 30-year-old woman who presented with hyperemesis and vomiting during the first trimester of pregnancy (hyperemesis gravidarum). Hyperemesis can lead to severe, symptomatic thiamine deficiency and to severe dehydration with prerenal azotemia.

Discussion: Wernicke encephalopathy is a rare complication of hyperemesis gravidarum. It should be diagnosed as early as possible to prevent long-term complications.

Publication types

  • Case Reports
  • English Abstract

MeSH terms

  • Adult
  • Antiemetics / therapeutic use
  • Diagnosis, Differential
  • Female
  • Fluid Therapy
  • Humans
  • Hyperemesis Gravidarum* / drug therapy
  • Infant, Newborn
  • Magnetic Resonance Imaging
  • Male
  • Potassium / therapeutic use
  • Pregnancy
  • Pregnancy Trimester, First
  • Thiamine / administration & dosage
  • Thiamine / therapeutic use
  • Time Factors
  • Treatment Outcome
  • Wernicke Encephalopathy / diagnosis
  • Wernicke Encephalopathy / drug therapy
  • Wernicke Encephalopathy / etiology*
  • Wernicke Encephalopathy / therapy

Substances

  • Antiemetics
  • Potassium
  • Thiamine