Late dofetilide-associated life-threatening proarrhythmia

Int J Cardiol. 2008 Jul 4;127(2):e54-6. doi: 10.1016/j.ijcard.2007.04.014. Epub 2007 Jun 27.

Abstract

This report is about a 62-year old male patient with an implantable cardioverter defibrillator (ICD) for patient activated termination of atrial fibrillation who experienced dofetilide-associated ventricular tachyarrhythmias and ICD-induced ventricular fibrillation six months after the initiation of the antiarrhythmic drug therapy.

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Anti-Arrhythmia Agents / adverse effects*
  • Atrial Fibrillation / therapy*
  • Defibrillators, Implantable / adverse effects*
  • Electrocardiography
  • Humans
  • Male
  • Middle Aged
  • Phenethylamines / adverse effects*
  • Sulfonamides / adverse effects*
  • Tachycardia, Ventricular / chemically induced*
  • Ventricular Fibrillation / etiology*

Substances

  • Anti-Arrhythmia Agents
  • Phenethylamines
  • Sulfonamides
  • dofetilide