Y791F RET mutation and early onset of medullary thyroid carcinoma in a Brazilian kindred: evaluation of phenotype-modifying effect of germline variants

Clin Endocrinol (Oxf). 2007 Nov;67(5):806-8. doi: 10.1111/j.1365-2265.2007.02964.x. Epub 2007 Jul 4.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Age of Onset
  • Brazil
  • Carcinoma, Medullary / genetics*
  • Child
  • Child, Preschool
  • Female
  • Germ-Line Mutation*
  • Humans
  • Male
  • Pedigree
  • Phenotype
  • Proto-Oncogene Proteins c-ret / genetics*
  • Thyroid Neoplasms / genetics*

Substances

  • Proto-Oncogene Proteins c-ret
  • RET protein, human