Cerebellar astrocytoma presenting with precocious puberty in a girl. Case report

J Neurosurg. 2007 Jul;107(1 Suppl):66-8. doi: 10.3171/PED-07/07/066.

Abstract

Central precocious puberty in girls is uncommon and tends to be idiopathic in most cases. In about 20 to 30% of cases there is an intracranial mass lesion. The common lesions are hypothalamic hamartomas, optic nerve gliomas, suprasellar arachnoid cysts, hydrocephalus, germinomas, and other sellar/suprasellar lesions. Central precocious puberty secondary to a cerebellar astrocytoma is extremely rare. The authors report the first case in a girl who presented with several episodes of bleeding per vaginum. There was no clinical or radiological evidence of raised intracranial pressure.

Publication types

  • Case Reports

MeSH terms

  • Astrocytoma / complications
  • Astrocytoma / diagnosis*
  • Astrocytoma / pathology
  • Astrocytoma / surgery
  • Cerebellar Neoplasms / complications
  • Cerebellar Neoplasms / diagnosis*
  • Cerebellar Neoplasms / pathology
  • Cerebellar Neoplasms / surgery
  • Cerebellum / pathology
  • Cerebellum / surgery
  • Child, Preschool
  • Diagnosis, Differential
  • Dominance, Cerebral
  • Estradiol / blood
  • Female
  • Gonadal Steroid Hormones / blood
  • Humans
  • Magnetic Resonance Imaging
  • Menstruation / physiology
  • Puberty, Precocious / etiology*

Substances

  • Gonadal Steroid Hormones
  • Estradiol