Effect of three bowel preparations on video-capsule endoscopy gastric and small-bowel transit time and completeness of the examination

Scand J Gastroenterol. 2007 Sep;42(9):1120-6. doi: 10.1080/00365520701251601.

Abstract

Objective: Video capsule endoscopy fails to visualize the caecum in about 20% of patients. The aim of this study was to investigate the effect of different bowel preparations on video capsule endoscopy gastric- (GTT) and small-bowel transit time (SBTT) and the rate of caecal visualization.

Material and methods: We retrospectively examined 186 consecutive capsule endoscopy videos undertaken over a 3-year period, excluding cases with diabetes mellitus or gastric surgery (n=28), cases with unknown bowel preparation and those with unreadable data CDs (n=27). Sixty-seven (36%) patients were prepared with a liquid diet (CL), 54 (29%) with sodium phosphate (PS) and 65 (35%) with polyethylene glycol (PEG). Two independent, experienced investigators examined the videos.

Results: No difference was found in GTT among CL, PS and PEG preparations (25, 6.7-116.2 min, 34.75, 4.1-125 min, 35, 6.1-128.6 min, respectively, p=0.29). The caecum was visualized in 56/67 (83.6%), 44/54 (81.5%) and 53/65 (81.5%) patients who received CL, PS and PEG, respectively (p=0.9). In the cases where capsule endoscopy reached the caecum, no difference was observed in SBTT among patients that received CL, PS and PEG (264.4+/-85.9 min, 296.7+/-79.5 min, 291.3+/-84 min, respectively, p=0.11).

Conclusions: Bowel preparations for capsule endoscopy do not have a significant effect on gastric and small-bowel video capsule transit time and the rate of caecum visualization.

MeSH terms

  • Adult
  • Aged
  • Capsule Endoscopy / standards*
  • Cathartics / administration & dosage*
  • Cohort Studies
  • Double-Blind Method
  • Endoscopy, Gastrointestinal / methods*
  • Enema / methods
  • Enema / standards
  • Female
  • Gastrointestinal Transit / physiology*
  • Humans
  • Male
  • Middle Aged
  • Observer Variation
  • Phosphates / administration & dosage
  • Polyethylene Glycols / administration & dosage
  • Retrospective Studies
  • Surface-Active Agents / administration & dosage

Substances

  • Cathartics
  • Phosphates
  • Surface-Active Agents
  • Polyethylene Glycols
  • sodium phosphate